| Display Channel | Digital Channel | Call Sign | Network | Nickname | Hours | Notes |
| KHQA-TV | HANNIBAL, MO | |||||
| 07-1 | 22.3 | CBS | CBS | "KHQA-TV 7" | ||
| 07-2 | 22.4 | ABC | ABC | "KHQA ABC 7.2" | ||
| 07-3 | 22.5 | Comet | Comet TV | |||
| 07-4 | 22.6 | ROAR | ROAR | |||
| WGEM-TV | QUINCY, IL | |||||
| 10-1 | 19.1 | WGEMNBC | NBC | "WGEM" | ||
| 10-2 | 19.2 | WGEM CW | CW+ | "Tri-States CW" | ||
| 10-3 | 19.3 | WGEMFOX | FOX | "WGEM FOX" | ||
| 10-4 | 19.4 | WGEMMe | Me-TV | |||
| K28JD-D | FORT MADISON, IA | |||||
| 12-01 | 28.3 | IowaPBS | PBS | "Iowa PBS" | ||
| K18NZ-D | KEOKUK, IA | |||||
| 12-01 | 18.3 | IowaPBS | PBS | "Iowa PBS" | ||
| K28JD-D | FORT MADISON, IA | |||||
| 12-02 | 28.4 | PBSKids | PBS Kids 24/7 | |||
| K18NZ-D | KEOKUK, IA | |||||
| 12-02 | 18.4 | PBSKids | PBS Kids 24/7 | |||
| K28JD-D | FORT MADISON, IA | |||||
| 12-03 | 28.5 | World | World Channel | |||
| K18NZ-D | KEOKUK, IA | |||||
| 12-03 | 18.5 | World | World Channel | |||
| K28JD-D | FORT MADISON, IA | |||||
| 12-04 | 28.6 | Create | Create | |||
| K18NZ-D | KEOKUK, IA | |||||
| 12-04 | 18.6 | Create | Create | |||
| K28JD-D | FORT MADISON, IA | |||||
| 12-99 | 28.99 | IRIS | Audio | "IRIS" | ||
| K18NZ-D | KEOKUK, IA | |||||
| 12-99 | 18.99 | IRIS | Audio | "IRIS" | ||
| K14SU-D | KEOKUK, IA | |||||
| 14-1 | 14.1001 | K14SU-D | 365BLK | |||
| 14-2 | 14.1002 | K14SU-D | Outlaw | |||
| 14-3 | 14.1003 | K14SU-D | Busted | |||
| 14-4 | 14.1004 | K14SU-D | Confess | |||
| 14-5 | 14.1005 | K14SU-D | Nosey | |||
| 14-6 | 14.1006 | K14SU-D | MovieSphere Gold | |||
| 14-7 | 14.1007 | K14SU-D | Fubo Sports | |||
| WTJR | QUINCY, IL | |||||
| 16-1 | 32.3 | WTJR DT | CTN | |||
| 16-2 | 32.4 | Lifesty | CTN Lifestyle | |||
| 16-3 | 32.5 | CTNi | CTNi | |||
| 16-4 | 32.6 | N2 | Newsmax2 | |||
| 16-5 | 32.7 | BIZ-TV | Biz TV | |||
| W17EH-D | QUINCY, IL | |||||
| 17-01 | 17.1 | W17EH | Binge TV | |||
| 17-02 | 17.2 | Bridge1 | Infomercials | |||
| 17-03 | 17.3 | Bridge2 | Infomercials | |||
| 17-04 | 17.4 | ACEtv | ACE TV | |||
| 17-05 | 17.5 | OAN | One America Plus | |||
| 17-06 | 17.6 | beIN | beIN Sports Xtra | |||
| 17-07 | 17.7 | Sales | Infomercials | |||
| 17-08 | 17.8 | BarkTV | Bark TV | |||
| 17-09 | 17.9 | RNTV | Right Now TV | |||
| 17-10 | 17.10 | FTF | FTF Sports | |||
| 17-11 | 17.11 | MTRSPT1 | MtrSpt1 | |||
| 17-12 | 17.12 | AWE | AWE Plus | |||
| 17-13 | 17.13 | NBT | National Black TV | |||
| 17-14 | 17.14 | ZLiving | Z Living | |||
| W27DF-D | QUINCY, IL | |||||
| 18-1 | 27.1 | W27DF-D | 3ABN | |||
| 18-2 | 27.2 | 3ABN-PR | [Blank] | |||
| 18-4 | 27.4 | 3ABN-ES | [Blank] | |||
| 18-5 | 27.5 | 3ABN-RD | 3ABN Radio | |||
| 18-6 | 27.6 | 3ABN-RL | 3ABN Radio Latino | |||
| 18-7 | 27.7 | Radio 7 | Radio 74 | |||
| WMEC | MACOMB, IL | |||||
| 22-1 | 36.3 | WMECHD | PBS | "WSIU" | ||
| 22-2 | 36.4 | WORLDSD | World Channel | |||
| 22-3 | 36.5 | CreatSD | Create | |||
| 22-4 | 36.6 | Kids247 | PBS Kids 24/7 | |||
| WQEC | QUINCY, IL | |||||
| 27-1 | 34.3 | WQECHD | PBS | "WSIU" | ||
| 27-2 | 34.4 | WORLDSD | World Channel | |||
| 27-3 | 34.5 | CreatSD | Create | |||
| 27-4 | 34.6 | Kids247 | PBS Kids 24/7 | |||
| WVDM-LD | QUINCY, IL | |||||
| 40-1 | 21.1001 | WVDM-LD | 365BLK | |||
| 40-2 | 21.1002 | WVDM-LD | Outlaw | |||
| 40-3 | 21.1003 | WVDM-LD | The First TV | |||
| 40-4 | 21.1004 | WVDM-LD | Busted | |||
| 40-5 | 21.1005 | WVDM-LD | Defy TV | |||
| 40-6 | 21.1006 | WVDM-LD | Infomercials | |||
| 40-7 | 21.1007 | WVDM-LD | Fubo Sports | |||